Commissions and Fees: ETFs typically trade by commission, however, TD Ameritrade offers access to an extensive list of commission-free ETFs. In general, an ETF tends to be more cost-efficient than an actively managed mutual fund, because of its indexed nature. This often results in lower fees. E*TRADE vs. TD Ameritrade - NerdWallet Feb 10, 2017 · E*TRADE and TD Ameritrade often top the pile of online brokers, making it tough for investors to decide between the two. You won’t pay activity or annual fees at either broker.